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Search Results to Linda R Watkins

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Watkins, Linda

One or more keywords matched the following items that are connected to Watkins, Linda

Item Type	Name
Academic Article	A peptide antagonist of the TLR4-MD2 interaction.
Academic Article	The cortical innate immune response increases local neuronal excitability leading to seizures.
Academic Article	Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta.
Academic Article	The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia.
Academic Article	Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats.
Academic Article	Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences.
Academic Article	Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity.
Academic Article	Toll-like receptor 4 in CNS pathologies.
Academic Article	Application of a novel in silico high-throughput screen to identify selective inhibitors for protein-protein interactions.
Academic Article	Sex and estradiol influence glial pro-inflammatory responses to lipopolysaccharide in rats.
Academic Article	(+)-naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats.
Academic Article	Opioid activation of toll-like receptor 4 contributes to drug reinforcement.
Academic Article	Blocking toll-like receptor 2 and 4 signaling during a stressor prevents stress-induced priming of neuroinflammatory responses to a subsequent immune challenge.
Academic Article	A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4.
Academic Article	Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4).
Academic Article	Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression.
Academic Article	Prior exposure to glucocorticoids sensitizes the neuroinflammatory and peripheral inflammatory responses to E. coli lipopolysaccharide.
Academic Article	Evidence that opioids may have toll-like receptor 4 and MD-2 effects.
Academic Article	Naloxone-precipitated morphine withdrawal behavior and brain IL-1? expression: comparison of different mouse strains.
Academic Article	An MD2 hot-spot-mimicking peptide that suppresses TLR4-mediated inflammatory response in vitro and in vivo.
Academic Article	Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice.
Academic Article	Morphine activates neuroinflammation in a manner parallel to endotoxin.
Academic Article	Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain.
Academic Article	Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving.
Concept	Toll-Like Receptor 4
Concept	Toll-Like Receptor 9
Concept	Toll-Like Receptor 2
Concept	Toll-Like Receptor 5
Academic Article	Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain.
Academic Article	In vivo veritas: (+)-Naltrexone's actions define translational importance: A letter in response to Skolnick et al. 'Translational potential of naloxone and naltrexone as TLR4 antagonists'.
Academic Article	Discovery of a novel site of opioid action at the innate immune pattern-recognition receptor TLR4 and its role in addiction.
Academic Article	Glial TLR4 signaling does not contribute to opioid-induced depression of respiration.
Academic Article	Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae.
Academic Article	Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain.
Academic Article	Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signaling.
Academic Article	Opioid-induced central immune signaling: implications for opioid analgesia.
Academic Article	Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists.
Academic Article	Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4.
Academic Article	DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling.
Academic Article	Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury.
Academic Article	Selection, Preparation, and Evaluation of Small- Molecule Inhibitors of Toll-Like Receptor 4.
Academic Article	HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia.
Grant	Targeting toll like receptor 4 (TLR4) and TLR2 to resolve EAE-associated paralysis, pain and cognitive deficits: efficacy of a clinically-relevant blood brain barrier permeable TLR4/TLR2 antagonist
Academic Article	Innate immune signaling in the ventral tegmental area contributes to drug-primed reinstatement of cocaine seeking.
Academic Article	Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats.
Academic Article	Dissecting the Innate Immune Recognition of Opioid Inactive Isomer (+)-Naltrexone Derived Toll-like Receptor 4 (TLR4) Antagonists.
Academic Article	Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling.
Academic Article	Methamphetamine Activates Toll-Like Receptor 4 to Induce Central Immune Signaling within the Ventral Tegmental Area and Contributes to Extracellular Dopamine Increase in the Nucleus Accumbens Shell.
Academic Article	Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain.
Academic Article	Suppression of active phase voluntary wheel running in male rats by unilateral chronic constriction injury: Enduring therapeutic effects of a brief treatment of morphine combined with TLR4 or P2X7 antagonists.
Academic Article	Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone.
Academic Article	Toll-like receptor 2 and 4 antagonism for the treatment of experimental autoimmune encephalomyelitis (EAE)-related pain.
Academic Article	Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats.
Academic Article	Toll-like receptor 4 antagonists reduce cocaine-primed reinstatement of drug seeking.

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Toll Like Receptor 1